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pilus assembly protein PilM
The type IV pilus assembly protein PilM is required for competency and pilus biogenesis [1-2]. It binds to PilN and ATP [3]. [1]. 8550460. Characterization of genes required for pilus expression in Pseudomonas syringae pathovar phaseolicola. Roine E, Nunn DN, Paulin L, Romantschuk M;. J Bacteriol. 1996;178:410-417. [2]. 16857013. Identification, subcellular localization and functional interactions of PilMNOWQ and PilA4 involved in transformation competency and pilus biogenesis in the thermophilic bacterium Thermus thermophilus HB27. Rumszauer J, Schwarzenlander C, Averhoff B;. FEBS J. 2006;273:3261-3272. [3]. 21596754. Structure of the PilM-PilN inner membrane type IV pilus biogenesis complex from Thermus thermophilus. Karuppiah V, Derrick JP;. J Biol Chem. 2011;286:24434-24442. (from Pfam)
type IV pilus biogenesis protein PilM
type IV pilus biogenesis protein PilM binds to PilB, PilT, and possibly PilC and that binding of PilN may modulate the interaction of PilM with PilB, PilT, and/or PilC
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