Protein Family Models for Protein (Select 502826623) - Protein Family Models

Select item 4263201.

methyltransferase domain-containing protein

This family appears to have methyltransferase activity. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF025217.5
Method:: HMM

Select item 4232842.

methyltransferase domain-containing protein

This family appears to be a methyltransferase domain. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF025033.5
Method:: HMM

Select item 4179133.

methyltransferase domain-containing protein

Members of this family are SAM dependent methyltransferases. (from Pfam)

GO Terms:

Molecular Function:: S-adenosylmethionine-dependent methyltransferase activity (GO:0008757)

Date:: 2024-08-14

Family Accession:: NF019846.5
Method:: HMM

Select item 4127494.

RMKL-like, methyltransferase domain

This domain is the methyltransferase domain found in ribosomal RNA large subunit methyltransferase K/L from Escherichia coli (RmlKL), tRNA (guanine(10)-N2)-dimethyltransferase from Methanocaldococcus jannaschii and similar proteins, which have a THUMP domain at the N-terminal [1-4]. [1]. 11295541. THUMP - a predicted RNA-binding domain shared by 4-thiouridine, pseudouridine synthases and RNA methylases. Aravind L, Koonin EV;. Trends Biochem Sci 2001;26:215-217. [2]. 16343540. Crystal structure of Bacillus anthracis ThiI, a tRNA-modifying enzyme containing the predicted RNA-binding THUMP domain. Waterman DG, Ortiz-Lombardia M, Fogg MJ, Koonin EV, Antson AA;. J Mol Biol. 2006;356:97-110. [3]. 17010378. Identification of Escherichia coli m2G methyltransferases: I. the ycbY gene encodes a methyltransferase specific for G2445 of the 23 S rRNA. Lesnyak DV, Sergiev PV, Bogdanov AA, Dontsova OA;. J Mol Biol. 2006;364:20-25. [4]. 22362734. Structure of the bifunctional methyltransferase YcbY (RlmKL) that adds the m7G2069 and m2G2445 modifications in Escherichia coli 23S rRNA. Wang KT, Desmolaize B, Nan J, Zhang XW, Li LF, Douthwaite S, Su XD;. Nucleic Acids Res. 2012;40:5138-5148. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF013347.5
Method:: HMM

Select item 4120305.

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)

Date:: 2024-08-14

Family Accession:: NF013315.5
Method:: HMM

Select item 4117226.

methyltransferase

This family includes a range of O-methyltransferases. These enzymes utilise S-adenosyl methionine. [1]. 8434913. Purification of a 40-kilodalton methyltransferase active in the aflatoxin biosynthetic pathway. Keller NP, Dischinger HC, Bhatnagar D, Cleveland TE, Ullah AH;. Appl Environ Microbiol 1993;59:479-484. (from Pfam)

GO Terms:

Molecular Function:: O-methyltransferase activity (GO:0008171)

Date:: 2024-10-16

Family Accession:: NF013087.5
Method:: HMM

Select item 4030097.