Protein Family Models

This family includes kinases that phosphorylate a variety of amino acid substrates, as well as uridylate kinase and carbamate kinase. This family includes: Aspartokinase EC:2.7.2.4, Swiss:P00561. Acetylglutamate kinase EC:2.7.2.8, Swiss:Q07905. Glutamate 5-kinase EC:2.7.2.11, Swiss:P07005. Uridylate kinase EC:2.7.4.-, Swiss:P29464. Carbamate kinase EC:2.7.2.2, Swiss:O96432. [1]. 10860751. The 1.5 A resolution crystal structure of the carbamate kinase-like carbamoyl phosphate synthetase from the hyperthermophilic Archaeon pyrococcus furiosus, bound to ADP, confirms that this thermostable enzyme is a carbamate kinase, and provides insight in. Ramon-Maiques S, Marina A, Uriarte M, Fita I, Rubio V;. J Mol Biol 2000;299:463-476. (from Pfam)

Date:

2024-10-16

glutamate 5-kinase catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate

Date:

2017-11-30

The glutamate 5-kinase ProB has an N-terminal kinase domain and a dispensable C-terminal PUA domain. ProB catalyzes the first step in proline biosynthesis from glutamate, and typically is subject to feedback inhibition by proline.

Gene:

proB

Date:

2024-05-30