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Probable addiction module antidote protein
This entry represents a helix-turn-helix domain that is found in the HI1420 protein. Members of this strictly bacterial protein family are small, at roughly 100 amino acids. The gene is almost invariably the downstream member of a gene pair. It is a predicted helix-turn-helix DNA-binding protein. These gene pairs, when found on the bacterial chromosome, are located often with prophage regions, but also both in integrated plasmid regions and in housekeeping gene regions. Analysis suggests that the gene pair may serve as an addiction module. (from Pfam)
addiction module antidote protein
Members of this strictly bacterial protein family are small, at roughly 100 amino acids. The gene is almost invariably the downstream member of a gene pair. It is a predicted DNA-binding protein from a clade within Pfam helix-turn-helix family PF01381. These gene pairs, when found on the bacterial chromosome, are located often with prophage regions, but also both in integrated plasmid regions and in housekeeping gene regions. Analysis suggests that the gene pair may serve as an addiction module.
DNA-binding protein
DNA-binding protein such as a helix-turn-helix transcriptional regulator, similar to Rhizobium addiction module antitoxin
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