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copper resistance protein B
This family consists of several bacterial copper resistance proteins. Copper is essential and serves as cofactor for more than 30 enzymes yet a surplus of copper is toxic and leads to radical formation and oxidation of biomolecules. Therefore, copper homeostasis is a key requisite for every organism. CopB serves to extrude copper when it approaches toxic levels [1]. [1]. 11696373. Tetrathiomolybdate inhibition of the Enterococcus hirae CopB copper ATPase. Bissig KD, Voegelin TC, Solioz M;. FEBS Lett 2001;507:367-370. (from Pfam)
copper resistance protein B is a P-type ATPase that acts as a resistance factor to copper ions by extruding copper when concentrations approach toxic levels
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