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carotenoid oxygenase family protein
This family represents a retinal pigment epithelial membrane receptor which is abundantly expressed in retinal pigment epithelium, and binds plasma retinal binding protein. The family also includes the sequence related neoxanthin cleavage enzyme in plants and lignostilbene-alpha,beta-dioxygenase in bacteria. [1]. 7633413. Molecular characterization of the human gene encoding an abundant 61 kDa protein specific to the retinal pigment epithelium. Nicoletti A, Wong DJ, Kawase K, Gibson LH, Yang-Feng TL, Richards JE, Thompson DA;. Hum Mol Genet 1995;4:641-649. (from Pfam)
carotenoid oxygenase family protein is a dioxygenase, such as Mycobacterium tuberculosis mitochondrial carotenoid-cleaving dioxygenase that catalyzes the oxidative cleavage of several carotenoids and apocarotenoids
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