Protein Family Models for Protein (Select 503564669) - Protein Family Models

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Links from Protein

Items: 6

Select item 4356471.

tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase Taw3

Gene:: taw3

GO Terms:

Molecular Function:: tRNA methyltransferase activity (GO:0008175)

Biological Process:: tRNA methylation (GO:0030488)

Biological Process:: wybutosine biosynthetic process (GO:0031591)

Date:: 2024-11-01

Family Accession:: NF047731.1
Method:: HMM

Select item 4136852.

tRNA-wybutosine modification methyltransferase TYW3

The methyltransferase TYW3 (tRNA-yW- synthesising protein 3) has been identified in yeast to be involved in wybutosine (yW) biosynthesis [1]. yW is a complexly modified guanosine residue that contains a tricyclic base and is found at the 3' position adjacent the anticodon of phenylalanine tRNA. TYW3 is an N-4 methylase that methylates yW-86 to yield yW-72 in an Ado-Met-dependent manner [1]. [1]. 16642040. Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. Noma A, Kirino Y, Ikeuchi Y, Suzuki T;. EMBO J. 2006; [Epub ahead of print] (from Pfam)

Date:: 2024-11-01

Family Accession:: NF014706.5
Method:: HMM

Select item 3905473.

new record, indexing in progress

Family Accession:

Select item 3496834.

new record, indexing in progress

Family Accession:

Select item 1839755.

hypothetical protein

Date:: 2020-10-26

Family Accession:: NF003265.0
Method:: HMM

Select item 1363236.

tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase

tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase belongs to the tRNA wybutosine-synthesizing 3 (TYW3) family and is a S-adenosyl-L-methionine (SAM)-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway; may methylate N-4 position of wybutosine-86 to produce wybutosine-72