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multiple antibiotic resistance regulatory protein MarB
The MarB protein is found in the multiple antibiotic resistance (mar) locus in Escherichia coli. The MarB protein is functionally uncharacterised. This family of proteins is found in bacteria. Proteins in this family are approximately 70 amino acids in length. There is a conserved GSDKSD sequence motif. [1]. 11897595. mar Operon involved in multidrug resistance of Enterobacter aerogenes. Chollet R, Bollet C, Chevalier J, Mallea M, Pages JM, Davin-Regli A;. Antimicrob Agents Chemother. 2002;46:1093-1097. [2]. 10856650. Prevalence of the multiple antibiotic resistance operon (marRAB) in the genus Salmonella. Kunonga NI, Sobieski RJ, Crupper SS;. FEMS Microbiol Lett. 2000;187:155-160. (from Pfam)
multiple antibiotic resistance protein MarB
multiple antibiotic resistance protein MarB is a small periplasmic protein that represses the marRAB promoter by an indirect mechanism, possibly involving a signal to one of the cytoplasmic regulators of that promoter
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