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DHHA2 domain-containing protein
This domain is often found adjacent to the DHH domain Pfam:PF01368 and is called DHHA2 for DHH associated domain. This domain is diagnostic of DHH subfamily 2 members [1]. The domain is about 120 residues long and contains a conserved DXK motif at its amino terminus. [1]. 9478130. A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease. Aravind L, Koonin EV;. Trends Biochem Sci 1998;23:17-19. (from Pfam)
DHH family phosphoesterase
It is predicted that this family of proteins all perform a phosphoesterase function. It included the single stranded DNA exonuclease RecJ. [1]. 9478130. A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease. Aravind L, Koonin EV;. Trends Biochem Sci 1998;23:17-19. (from Pfam)
DHH family phosphoesterase such as Saccharomyces cerevisiae exopolyphosphatase Ppx1p that catalyzes the degradation of inorganic polyphosphates
manganese-dependent inorganic pyrophosphatase
Catalyzes the hydrolysis of pyrophosphate to phosphate
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