Protein Family Models

This large family of proteins contains several highly conserved charged amino acids, suggesting this may be an enzymatic domain (Bateman A pers. obs). The family includes SanA Swiss:P33017 that is involved in Vancomycin resistance [1]. This protein may be involved in murein synthesis [2]. [1]. 8550448. Amplification of a novel gene, sanA, abolishes a vancomycin-sensitive defect in Escherichia coli. Rida S, Caillet J, Alix JH;. J Bacteriol 1996;178:94-102. [2]. 9738879. The sfiX, rfe and metN genes of Salmonella typhimurium and their involvement in the His(c) pleiotropic response. Mouslim C, Cano DA, Casadesus J;. Mol Gen Genet 1998;259:46-53. (from Pfam)

Date:

2024-10-16

vancomycin high temperature exclusion protein similar to Escherichia coli SanA, which participates in the barrier function of the cell envelope

Date:

2017-09-12

Gene:

sanA

Date:

2020-10-26