Protein Family Models

This domain is found in proteins from bacteria and archaea, including Inner membrane protein YgaP from Escherichia coli, a membrane protein with a rhodanese domain (Pfam: PF00581) that may have sulfurtransferase activity. YgaP adopts a dimeric assembly. This entry represents the transmembrane domain. It consist of two slightly tilted alpha-helices [1]. [1]. 24958726. Solution NMR structure and functional analysis of the integral membrane protein YgaP from Escherichia coli. Eichmann C, Tzitzilonis C, Bordignon E, Maslennikov I, Choe S, Riek R;. J Biol Chem. 2014;289:23482-23503. (from Pfam)

Date:

2024-10-16

Rhodanese has an internal duplication. This Pfam represents a single copy of this duplicated domain. The domain is found as a single copy in other proteins, including phosphatases and ubiquitin C-terminal hydrolases. Crystal structure. [1]. 8702871. Active site structural features for chemically modified forms of rhodanese. Gliubich F, Gazerro M, Zanotti G, Delbono S, Bombieri G, Berni R;. J Biol Chem 1996;271:21054-21061. (from Pfam)

Date:

2024-10-16

rhodanese family protein containing rhodanese homology and DUF2892 domains, similar to Escherichia coli inner membrane protein YgaP

Date:

2020-07-27