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tRNA pseudouridine(13) synthase TruD
TruD is responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs [1]. The structure of TruD reveals an overall V-shaped molecule which contains an RNA-binding cleft [2]. [1]. 12756329. A novel unanticipated type of pseudouridine synthase with homologs in bacteria, archaea, and eukarya. Kaya Y, Ofengand J;. RNA 2003;9:711-721. [2]. 15135053. X-ray structure of tRNA pseudouridine synthase TruD reveals an inserted domain with a novel fold. Ericsson UB, Nordlund P, Hallberg BM;. FEBS Lett 2004;565:59-64. (from Pfam)
tRNA pseudouridine(13) synthase TruD catalyzes the isomerization of uridines at positions 13 in tRNA to pseudouridines
an EGAD loading error caused one member to be called surE, but that's an adjacent gene. MJ11364 is a strong partial match from 50 to 230 aa.
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