Protein Family Models

Members of this family belong to Glycosyltransferase family 25 [1] This is a family of glycosyltransferases involved in lipopolysaccharide (LPS) biosynthesis. These enzymes catalyse the transfer of various sugars onto the growing LPS chain during its biosynthesis. [1]. 9334165. A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities. Campbell JA, Davies GJ, Bulone V, Henrissat B;. Biochem J 1997;326:929-939. [2]. 8817494. Molecular analysis of a locus for the biosynthesis and phase-variable expression of the lacto-N-neotetraose terminal lipopolysaccharide structure in Neisseria meningitidis. Jennings MP, Hood DW, Peak IR, Virji M, Moxon ER;. Mol Microbiol 1995;18:729-740. [3]. 7964493. Genetic locus for the biosynthesis of the variable portion of Neisseria gonorrhoeae lipooligosaccharide. Gotschlich EC;. J Exp Med 1994;180:2181-2190. [4]. 1956289. Molecular cloning of a gene involved in lipooligosaccharide biosynthesis and virulence expression by Haemophilus influenzae type B. Cope LD, Yogev R, Mertsola J, Latimer JL, Hanson MS, McCracken GH Jr, Hansen EJ;. Mol Microbiol 1991;5:1113-1124. (from Pfam)

Date:

2024-10-16

glycosyltransferase family 25 protein may be involved in lipopolysaccharide (LPS) biosynthesis, facilitating the transfer of one of a variety of sugars onto a growing LPS chain, such as lacto-N-neotetraose biosynthesis glycosyltransferase LgtB, which adds the second galactose to the lacto-N-tetraose chain in lipooligosaccharide (LOS)

Date:

2021-01-22