Protein Family Models

This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyses the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase. [1]. 9047339. Cloning, and molecular characterization of the GCV1 gene encoding the glycine cleavage T-protein from Saccharomyces cerevisiae. McNeil JB, Zhang F, Taylor BV, Sinclair DA, Pearlman RE, Bognar AL;. Gene 1997;186:13-20. (from Pfam)

Date:

2024-10-16

This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyses the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase. [1]. 9047339. Cloning, and molecular characterization of the GCV1 gene encoding the glycine cleavage T-protein from Saccharomyces cerevisiae. McNeil JB, Zhang F, Taylor BV, Sinclair DA, Pearlman RE, Bognar AL;. Gene 1997;186:13-20. (from Pfam)

Date:

2024-10-16

glycine cleavage system aminomethyltransferase GcvT is a component of glycine cleavage system that catalyzes the degradation of glycine

Date:

2023-03-01

Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein

Gene:

gcvT

Date:

2020-10-26

The glycine cleavage system T protein (GcvT) is also known as aminomethyltransferase (EC 2.1.2.10). It works with the H protein (GcvH), the P protein (GcvP), and lipoamide dehydrogenase. The reported sequence of the member from Aquifex aeolicus starts about 50 residues downstream of the start of other members of the family (perhaps in error); it scores below the trusted cutoff. Eukaryotic forms are mitochondrial and have an N-terminal transit peptide.

Gene:

gcvT

Date:

2021-04-27