Protein Family Models for Protein (Select 505126238) - Protein Family Models

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Items: 4

Select item 4111351.

Phosphorylase superfamily

Members of this family include: purine nucleoside phosphorylase (PNP) Uridine phosphorylase (UdRPase) 5'-methylthioadenosine phosphorylase (MTA phosphorylase) [1]. 7920254. Unexpected sequence similarity between nucleosidases and phosphoribosyltransferases of different specificity. Mushegian AR, Koonin EV;. Protein Sci 1994;3:1081-1088. [2]. 9351810. The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology. Mao C, Cook WJ, Zhou M, Koszalka GW, Krenitsky TA, Ealick SE;. Structure 1997;5:1373-1383. (from Pfam)

GO Terms:

Molecular Function:: catalytic activity (GO:0003824)

Biological Process:: nucleoside metabolic process (GO:0009116)

Date:: 2024-10-16

Family Accession:: NF013232.5
Method:: HMM

Select item 3898752.

new record, indexing in progress

Family Accession:

Select item 3475893.

new record, indexing in progress

Family Accession:

Select item 2853794.

nucleoside phosphorylase

nucleoside phosphorylase similar to uridine phosphorylase (UP), a key enzyme in the pyrimidine salvage pathway that catalyzes the reversible phosphorolysis of uridine or 2'-deoxyuridine to uracil and ribose 1-phosphate or 2'-deoxyribose 1-phosphate