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single-stranded DNA-binding protein
This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA. [1]. 9192620. Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-A resolution. Raghunathan S, Ricard CS, Lohman TM, Waksman G;. Proc Natl Acad Sci U S A 1997;94:6652-6657. [2]. 9033597. Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4 A resolution. Yang C, Curth U, Urbanke C, Kang C;. Nat Struct Biol 1997;4:153-157. [3]. 9271227. A common core for binding single-stranded DNA: structural comparison of the single-stranded DNA-binding proteins (SSB) from E. coli and human mitochondria. Webster G, Genschel J, Curth U, Urbanke C, Kang C, Hilgenfeld R;. FEBS Lett 1997;411:313-316. (from Pfam)
single-stranded DNA (ssDNA)-binding protein plays a key role in DNA replication, recombination, and repair
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