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DnaA ATPase domain-containing protein
This entry represents the ATPAse domain of DnaA and similar proteins. [1]. 12234917. The structure of bacterial DnaA: implications for general mechanisms underlying DNA replication initiation. Erzberger JP, Pirruccello MM, Berger JM;. EMBO J. 2002;21:4763-4773. (from Pfam)
DnaA regulatory inactivator Hda
Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP.
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