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Links from Protein

Items: 16

1.

2-oxoglutarate dehydrogenase family protein

2-oxoglutarate dehydrogenase family protein, such as 2-oxoglutarate dehydrogenase subunit E1 that catalyzes the decarboxylation of 2-oxoglutarate and the formation of TPP-hydroxysuccinate

Date:
2024-08-21
Family Accession:
11426267
Method:
Sparcle
2.

2-oxoglutarate dehydrogenase E1 subunit family protein

This domain is found at the N-terminus of 2-oxoglutarate dehydrogenases. (from Pfam)

Date:
2024-11-24
Family Accession:
NF027404.5
Method:
HMM
3.

2-oxoglutarate dehydrogenase C-terminal

OxoGdeHyase_C is a family found immediately C-terminal to Transket_pyr, Pfam:PF02779. It is found at the C-terminus of 2-oxoglutarate dehydrogenase. (from Pfam)

Date:
2024-08-14
Family Accession:
NF028180.5
Method:
HMM
4.

Transketolase, pyrimidine binding domain

This family includes transketolase enzymes, pyruvate dehydrogenases, and branched chain alpha-keto acid decarboxylases. [1]. 8176731. Refined structure of transketolase from Saccharomyces cerevisiae at 2.0 A resolution. Nikkola M, Lindqvist Y, Schneider G;. J Mol Biol 1994;238:387-404. [2]. 1628611. Three-dimensional structure of transketolase, a thiamine diphosphate dependent enzyme, at 2.5 A resolution. Lindqvist Y, Schneider G, Ermler U, Sundstrom M;. EMBO J 1992;11:2373-2379. (from Pfam)

Date:
2024-10-16
Family Accession:
NF014798.5
Method:
HMM
5.

thiamine pyrophosphate-dependent enzyme

This family uses thiamine pyrophosphate as a cofactor. This family includes pyruvate dehydrogenase, 2-oxoglutarate dehydrogenase and 2-oxoisovalerate dehydrogenase. (from Pfam)

GO Terms:
Molecular Function:
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (GO:0016624)
Date:
2024-08-14
Family Accession:
NF012880.5
Method:
HMM
6.
new record, indexing in progress
Family Accession:
7.
new record, indexing in progress
Family Accession:
8.
new record, indexing in progress
Family Accession:
9.
new record, indexing in progress
Family Accession:
10.
new record, indexing in progress
Family Accession:
11.
new record, indexing in progress
Family Accession:
12.
new record, indexing in progress
Family Accession:
13.
new record, indexing in progress
Family Accession:
14.

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit

kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate

GO Terms:
Molecular Function:
oxoglutarate dehydrogenase (succinyl-transferring) activity (GO:0004591)
Biological Process:
tricarboxylic acid cycle (GO:0006099)
Molecular Function:
acyltransferase activity (GO:0016746)
Molecular Function:
thiamine pyrophosphate binding (GO:0030976)
Date:
2021-08-12
Family Accession:
NF008907.0
Method:
HMM
15.

2-oxoglutarate dehydrogenase E1 component

The 2-oxoglutarate dehydrogenase complex consists of this thiamine pyrophosphate-binding subunit (E1), dihydrolipoamide succinyltransferase (E2), and lipoamide dehydrogenase (E3). The E1 ortholog from Corynebacterium glutamicum is unusual in having an N-terminal extension that resembles the dihydrolipoamide succinyltransferase (E2) component of 2-oxoglutarate dehydrogenase.

Gene:
sucA
GO Terms:
Molecular Function:
oxoglutarate dehydrogenase (succinyl-transferring) activity (GO:0004591)
Biological Process:
tricarboxylic acid cycle (GO:0006099)
Molecular Function:
thiamine pyrophosphate binding (GO:0030976)
Cellular Component:
oxoglutarate dehydrogenase complex (GO:0045252)
Date:
2024-06-21
Family Accession:
TIGR00239.1
Method:
HMM
16.

2-oxoglutarate dehydrogenase E1 component

GO Terms:
Molecular Function:
oxoglutarate dehydrogenase (succinyl-transferring) activity (GO:0004591)
Biological Process:
tricarboxylic acid cycle (GO:0006099)
Molecular Function:
thiamine pyrophosphate binding (GO:0030976)
Date:
2021-07-23
Family Accession:
NF006914.0
Method:
HMM
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