Protein Family Models

FlgT_N is the N-terminal domain of a family of flagellar proteins that make up part of the basal body of the flagellum. The flagellum is a large macromolecular assembly composed of three major parts: the basal body, the hook, and the filament. The basal body has two unique ring structures, the T ring and the H ring. FlgT is required to form and stabilise both ring structures. FlgT-N contributes to the construction of the H-ring structure, and adopts a two-layer alpha-beta sandwich architecture composed of a four-stranded anti-parallel beta-sheet and two alpha helices [1]. [1]. 23530206. Insight into the assembly mechanism in the supramolecular rings of the sodium-driven Vibrio flagellar motor from the structure of FlgT. Terashima H, Li N, Sakuma M, Koike M, Kojima S, Homma M, Imada K;. Proc Natl Acad Sci U S A. 2013;110:6133-6138. (from Pfam)

Date:

2024-10-16

FlgT_M is the middle region of a family of flagellar proteins that make up part of the basal body of the flagellum. The flagellum is a large macromolecular assembly composed of three major parts: the basal body, the hook, and the filament. The basal body has two unique ring structures, the T ring and the H ring. FlgT is required to form and stabilise both ring structures. FlgT-N and FlgT-M are thought to be involved in the H-ring and the T-ring formation, respectively. and FlgT-M is also required for the stable association of FlgT with the basal body [1]. [1]. 23530206. Insight into the assembly mechanism in the supramolecular rings of the sodium-driven Vibrio flagellar motor from the structure of FlgT. Terashima H, Li N, Sakuma M, Koike M, Kojima S, Homma M, Imada K;. Proc Natl Acad Sci U S A. 2013;110:6133-6138. (from Pfam)

Date:

2024-10-16

FlgT_C is the C-terminal domain of a family of flagellar proteins that make up part of the basal body of the flagellum. The flagellum is a large macromolecular assembly composed of three major parts: the basal body, the hook, and the filament. The basal body has two unique ring structures, the T ring and the H ring. FlgT is required to form and stabilise both ring structures. FlgT_C is not essential but stabilises the H-ring structure. [1]. [1]. 23530206. Insight into the assembly mechanism in the supramolecular rings of the sodium-driven Vibrio flagellar motor from the structure of FlgT. Terashima H, Li N, Sakuma M, Koike M, Kojima S, Homma M, Imada K;. Proc Natl Acad Sci U S A. 2013;110:6133-6138. (from Pfam)

Date:

2024-10-16

flagellar assembly protein FlgT is required to form and stabilize the two unique basal body ring structures, the T ring and the H ring, of the sodium-driven flagellar motor

Date:

2021-06-28