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GNAT family N-acetyltransferase
This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. [1]. 9175471. GCN5-related histone N-acetyltransferases belong to a diverse superfamily that includes the yeast SPT10 protein. Neuwald AF, Landsman D;. Trends Biochem Sci 1997;22:154-155. [2]. 11893502. A second catalytic domain in the Elp3 histone acetyltransferases: a candidate for histone demethylase activity?. Chinenov Y;. Trends Biochem Sci 2002;27:115-117. (from Pfam)
This domain catalyses N-acetyltransferase reactions. (from Pfam)
YiiD C-terminal domain-containing protein
This entry consists of a broadly distributed uncharacterised domain often found as a standalone protein. The member from Shewanella oneidensis is described from crystallography work as a putative thioesterase because it belongs to the HotDog clan of enzymes. About half of the members of this family are fused to an Acetyltransf_1 domain Pfam:PF00583. (from Pfam)
bifunctional GNAT family N-acetyltransferase/hotdog fold thioesterase
bifunctional GNAT family N-acetyltransferase/hotdog fold thioesterase containing an N-terminal domain that may catalyze the transfer of an acetyl group from acetyl-CoA to a substrate and a C-terminal thioesterase domain, similar to Escherichia coli putative acetyltransferase YiiD
putative thioesterase domain
This family consists of a broadly distributed uncharacterized domain found often as a standalone protein. The member from Shewanella oneidensis, PDB|1T82_A (Forouhar, et al., unpublished) is described from crystallography work as a putative thioesterase. About half of the members of this family are fused to an Acetyltransf_1 domain (PFAM model PF00583). The function of this protein is unknown.
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