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Glutamine amidotransferase domain
This domain is a class-II glutamine amidotransferase domain found in a variety of enzymes, such as asparagine synthetase and glutamine--fructose-6-phosphate transaminase. (from Pfam)
This domain is a class-II glutamine amidotransferase domain found in a variety of enzymes such as asparagine synthetase and glutamine-fructose-6-phosphate transaminase. (from Pfam)
class II glutamine amidotransferase
This family captures members that are not found in Pfam:PF00310. (from Pfam)
amidophosphoribosyltransferase
Alternate name: glutamine phosphoribosylpyrophosphate (PRPP) amidotransferase.
amidophosphoribosyltransferase catalyzes the conversion of 5-phosphoribosyl-1-pyrophosphate (PRPP) into 5-phosphoribosyl-1-amine (PRA) by using the ammonia group from a glutamine side-chain, which is the committing step in de novo purine synthesis
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