Protein Family Models for Protein (Select 515644747) - Protein Family Models

Select item 4258261.

This domain is found in Enoyl-(Acyl carrier protein) reductases. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF024950.5
Method:: HMM

Select item 4213452.

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group [1]. [1]. 23790488. Structural and stereochemical analysis of a modular polyketide synthase ketoreductase domain required for the generation of a cis-alkene. Bonnett SA, Whicher JR, Papireddy K, Florova G, Smith JL, Reynolds KA;. Chem Biol. 2013;20:772-783. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF020243.5
Method:: HMM

Select item 4113073.

SDR family NAD(P)-dependent oxidoreductase

This family contains a wide variety of dehydrogenases. [1]. 9735295. The refined crystal structure of Drosophila lebanonensis alcohol dehydrogenase at 1.9 A resolution. Benach J, Atrian S, Gonzalez-Duarte R, Ladenstein R;. J Mol Biol 1998;282:383-399. [2]. 10387002. Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis. Yamashita A, Kato H, Wakatsuki S, Tomizaki T, Nakatsu T, Nakajima K, Hashimoto T, Yamada Y, Oda J;. Biochemistry 1999;38:7630-7637. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF012334.5
Method:: HMM

Select item 4000274.