Protein Family Models for Protein (Select 515656577) - Protein Family Models

Select item 4306681.

AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA domains in proteins ranging from archaeal to fungi, plants and mammals. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF027519.5
Method:: HMM

Select item 4235452.

MgsA AAA+ ATPase C terminal

The MgsA protein possesses DNA-dependent ATPase and ssDNA annealing activities [1]. MgsA contributes to the recovery of stalled replication forks and therefore prevents genomic instability caused by aberrant DNA replication [1]. Additionally, MgsA may play a role in chromosomal segregation [1]. This is consistent with a report that MgsA co-localises with the replisome and affects chromosome segregation [1]. This domain represents the C terminal region of MgsA. [1]. 15743409. Functional overlap between RecA and MgsA (RarA) in the rescue of stalled replication forks in Escherichia coli. Shibata T, Hishida T, Kubota Y, Han YW, Iwasaki H, Shinagawa H;. Genes Cells. 2005;10:181-191. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF023428.5
Method:: HMM

Select item 4169353.

AAA family ATPase

This Pfam entry includes some of the AAA proteins not detected by the Pfam:PF00004 model. [1]. 7646486. A 200-amino acid ATPase module in search of a basic function. Confalonieri F, Duguet M;. Bioessays 1995;17:639-650. A large extension of the family. [2]. 9927482. AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Neuwald AF, Aravind L, Spouge JL, Koonin EV;. Genome Res 1999;9:27-43. (from Pfam)

GO Terms:

Molecular Function:: ATP binding (GO:0005524)

Molecular Function:: ATP hydrolysis activity (GO:0016887)

Date:: 2024-10-16

Family Accession:: NF019348.5
Method:: HMM

Select item 4153044.

Holliday junction DNA helicase RuvB P-loop domain

The RuvB protein makes up part of the RuvABC revolvasome which catalyses the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalysed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein [1]. This family contains the N-terminal region of the protein. [1]. 12423347. The RuvABC resolvasome. Dickman MJ, Ingleston SM, Sedelnikova SE, Rafferty JB, Lloyd RG, Grasby JA, Hornby DP;. Eur J Biochem 2002;269:5492-5501. (from Pfam)

GO Terms:

Biological Process:: DNA repair (GO:0006281)

Biological Process:: DNA recombination (GO:0006310)

Molecular Function:: four-way junction helicase activity (GO:0009378)

Date:: 2024-10-16

Family Accession:: NF017321.5
Method:: HMM

Select item 4116215.

AAA family ATPase

AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes [2]. [1]. 7646486. A 200-amino acid ATPase module in search of a basic function. Confalonieri F, Duguet M;. Bioessays 1995;17:639-650. A large extension of the family. [2]. 9927482. AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Neuwald AF, Aravind L, Spouge JL, Koonin EV;. Genome Res 1999;9:27-43. (from Pfam)

GO Terms:

Molecular Function:: ATP binding (GO:0005524)

Molecular Function:: ATP hydrolysis activity (GO:0016887)

Date:: 2024-10-16

Family Accession:: NF012234.5
Method:: HMM

Select item 4032016.