Protein Family Models for Protein (Select 515953460) - Protein Family Models

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Links from Protein

Items: 6

Select item 4118781.

This family includes a diverse range of phosphoesterases [1], including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD Swiss:P13457 or yeast MRE11 Swiss:P32829. The most conserved regions in this superfamily centre around the metal chelating residues. [1]. 9685491. Phosphoesterase domains associated with DNA polymerases of diverse origins. Aravind L, Koonin EV;. Nucleic Acids Res 1998;26:3746-3752. (from Pfam)

GO Terms:

Molecular Function:: hydrolase activity (GO:0016787)

Date:: 2024-10-16

Family Accession:: NF012376.5
Method:: HMM

Select item 3883792.

new record, indexing in progress

Family Accession:

Select item 3570353.

new record, indexing in progress

Family Accession:

Select item 3471024.

new record, indexing in progress

Family Accession:

Select item 1080615.

3',5'-cyclic-AMP phosphodiesterase

3',5'-cyclic-AMP phosphodiesterase catalyzes the hydrolysis of adenosine 3',5'-cyclic phosphate (cAMP) to form adenosine 5'-phosphate (5'-AMP); belongs to metallophosphatase (MPP) superfamily, whose members contain an active site consisting of two metal ions (usually manganese, iron, or zinc)