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hemimethylated DNA-binding YccV-like domain-containing protein
YccV is a hemimethylated DNA binding protein which has been shown to regulate dnaA gene expression [1]. The structure of one of the hypothetical proteins in this family has been solved and it forms a beta sheet structure with a terminating alpha helix. [1]. 12700277. Isolation of a new hemimethylated DNA binding protein which regulates dnaA gene expression. d'Alencon E, Taghbalout A, Bristow C, Kern R, Aflalo R, Kohiyama M;. J Bacteriol. 2003;185:2967-2971. (from Pfam)
heat shock protein HspQ
Although previously described as a hemimethylated DNA-binding protein, YccV, this protein now is thought to act as a heat shock protein that interacts with Lon protease.
heat shock protein HspQ is involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress
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