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nickel-binding protein
This family of proteins is found in prokaryotes, including the nickel responsive protein SCO4226 from Streptomyces coelicolor (Swiss:Q9FCE4). SCO4226 adopts a dimeric configuration able to bind four nickel ions, with each monomer showing a typical ferredoxin-like fold with five beta-strands packing against two alpha-helices. It seems to play a role in cellular nickel homeostasis, detoxification, and/or nickel utilization in specialised cytoplasmic compartment [1]. [1]. 25285530. Streptomyces coelicolor SCO4226 is a nickel binding protein. Lu M, Jiang YL, Wang S, Jin H, Zhang RG, Virolle MJ, Chen Y, Zhou CZ;. PLoS One. 2014;9:e109660. (from Pfam)
DUF4242 domain-containing protein
DUF4242 domain-containing protein similar to Streptomyces coelicolor SCO4226, a nickel binding protein that is probably required for nickel sequestration and/or detoxification
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