Protein Family Models

RsbU is a phosphoserine phosphatase which acts as a positive regulator of the general stress-response factor of gram positive organisms, sigma-B. The phosphatase activity of RsbU is stimulated by association with the RsbT kinase. Deletions in the N terminal domain are deleterious to the activity of RsbU [1]. [1]. 15263010. Functional and structural characterization of RsbU, a stress signaling protein phosphatase 2C. Delumeau O, Dutta S, Brigulla M, Kuhnke G, Hardwick SW, Volker U, Yudkin MD, Lewis RJ;. J Biol Chem. 2004;279:40927-40937. (from Pfam)

Date:

2024-10-16

This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments [1]. [1]. 8830262. Structure and function of the Bacillus SpoIIE protein and its localization to sites of sporulation septum assembly. Barak I, Behari J, Olmedo G, Guzman P, Brown DP, Castro E, Walker D, Westpheling J, Youngman P;. Mol Microbiol 1996;19:1047-1060. (from Pfam)

Date:

2024-10-16

RsbU_N and RsbU domain-containing protein

Date:

2017-03-02