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TrmH family RNA methyltransferase
This family of proteins probably use S-AdoMet. [1]. 8265370. SpoU protein of Escherichia coli belongs to a new family of putative rRNA methylases. Koonin EV, Rudd KE;. Nucleic Acids Res 1993;21:5519-5519. [2]. 9321663. The spoU gene of escherichia coli , the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2 ' - O -methyltransferase activity. Persson BC, Jager G, Gustafsson C;. Nucleic Acids Res 1997;25:4093-4097. (from Pfam)
tRNA (uridine(34)/cytosine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase TrmL
tRNA (cytidine(34)-2'-O)-methyltransferase
tRNA (cytidine(34)-2'-O)-methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine to the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA)
TrmL (previously YibK) is responsible for 2'-O-methylation at tRNA(Leu) position 34.
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