Protein Family Models for Protein (Select 517262660) - Protein Family Models

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Items: 4

Select item 4135631.

prepilin peptidase

Peptidase A24, or the prepilin peptidase as it is also known, processes the N-terminus of the prepilins [1]. The processing is essential for the correct formation of the pseudopili of type IV bacterial protein secretion. The enzyme is found across eubacteria and archaea [2]. [1]. 10625704. The type 4 prepilin peptidases comprise a novel family of aspartic acid proteases. LaPointe CF, Taylor RK;. J Biol Chem 2000;275:1502-1510. [2]. 12813086. Archaeal homolog of bacterial type IV prepilin signal peptidases with broad substrate specificity. Albers SV, Szabo Z, Driessen AJ;. J Bacteriol 2003;185:3918-3925. (from Pfam)

GO Terms:

Molecular Function:: aspartic-type endopeptidase activity (GO:0004190)

Cellular Component:: membrane (GO:0016020)

Date:: 2024-10-16

Family Accession:: NF013632.5
Method:: HMM

Select item 3901502.

new record, indexing in progress

Family Accession:

Select item 3478823.

new record, indexing in progress

Family Accession:

Select item 2578564.

A24 family peptidase

A24 family peptidase such as prepilin peptidase, which processes type 4 pilin precursor proteins (prepilins) to their mature forms by removal of leader peptides