Protein Family Models

Date:

2024-08-14

This domain is a DNA-binding helix-turn-helix domain. (from Pfam)

Date:

2024-08-14

The TOBE domain [1] (Transport-associated OB) always occurs as a dimer as the C-terminal strand of each domain is supplied by the partner. Probably involved in the recognition of small ligands such as molybdenum (eg Swiss:P46930) and sulfate (Swiss:P16676). Found in ABC transporters immediately after the ATPase domain. [1]. 10829230. Protein fold recognition using sequence profiles and its application in structural genomics. Koonin EV, Wolf YI, Aravind L;. Adv Protein Chem 2000;54:245-275. (from Pfam)

Date:

2024-10-16

Date:

2024-08-14

An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This HMM represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This HMM identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (PF00376).

Date:

2021-04-27

TOBE (Transport-associated OB) domain-containing protein is also known as molybdopterin-binding protein that may be involved in the recognition of small ligands such as molybdenum and sulfate

Date:

2024-12-23

This model describes a multigene family of molybdenum-pterin binding proteins of about 70 amino acids in Clostridium pasteurianum, as a tandemly-repeated domain C-terminal to an unrelated domain in ModE, a molybdate transport gene repressor of E. coli, and in single or tandemly paired domains in several related proteins.

Date:

2024-06-12