Protein Family Models for Protein (Select 518093896) - Protein Family Models

Select item 4110981.

aminotransferase class V-fold PLP-dependent enzyme

This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF012488.5
Method:: HMM

Select item 4110372.

aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme

GO Terms:

Biological Process:: biosynthetic process (GO:0009058)

Molecular Function:: pyridoxal phosphate binding (GO:0030170)

Date:: 2024-08-14

Family Accession:: NF012382.5
Method:: HMM

Select item 4110193.

PLP-dependent transferase

This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor. [1]. 8831789. Crystal structure of the pyridoxal-5'-phosphate dependent cystathionine beta-lyase from Escherichia coli at 1.83 A. Clausen T, Huber R, Laber B, Pohlenz HD, Messerschmidt A;. J Mol Biol 1996;262:202-224. [2]. 9843488. Crystal structure of Escherichia coli cystathionine gamma-synthase at 1.5 A resolution. Clausen T, Huber R, Prade L, Wahl MC, Messerschmidt A;. EMBO J 1998;17:6827-6838. (from Pfam)

GO Terms:

Biological Process:: transsulfuration (GO:0019346)

Molecular Function:: pyridoxal phosphate binding (GO:0030170)

Date:: 2024-10-16

Family Accession:: NF013237.5
Method:: HMM

Select item 4110184.

DegT/DnrJ/EryC1/StrS family aminotransferase

The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA Swiss:P72454, StsC Swiss:P77952 and StsS [1]. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyses the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin [1]. [1]. 9238101. Identification of stsC, the gene encoding the L-glutamine:scyllo-inosose aminotransferase from streptomycin-producing Streptomycetes. Ahlert J, Distler J, Mansouri K, Piepersberg W;. Arch Microbiol 1997;168:102-113. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF013227.5
Method:: HMM

Select item 3887515.