Protein Family Models

Cytochrome c oxidase (COX) is a multi-subunit enzyme complex that catalyses the final step of electron transfer through the respiratory chain on the mitochondrial inner membrane. This family is composed of cytochrome c oxidase subunit 4 from prokaryotes. [1]. 8638158. The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A. Tsukihara T, Aoyama H, Yamashita E, Tomizaki T, Yamaguchi H, Shinzawa-Itoh K, Nakashima R, Yaono R, Yoshikawa S;. Science 1996;272:1136-1144. (from Pfam)

Date:

2024-10-16

Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant.

Gene:

cyoD

Date:

2022-10-11

cytochrome o ubiquinol/quinol oxidase subunit IV such as cytochrome o ubiquinol oxidase subunit IV that is a component of the terminal oxidase of the aerobic respiratory chain that has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron

Date:

2019-09-10