Protein Family Models for Protein (Select 521078936) - Protein Family Models

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Items: 5

Select item 4109691.

dUTPase

dUTPase hydrolyses dUTP to dUMP and pyrophosphate. [1]. 1311056. Crystal structure of a dUTPase. Cedergren-Zeppezauer ES, Larsson G, Nyman PO, Dauter Z, Wilson KS;. Nature 1992;355:740-743. [2]. 8805593. Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits. Mol CD, Harris JM, McIntosh EM, Tainer JA;. Structure 1996;4:1077-1092. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF012895.5
Method:: HMM

Select item 3899662.

new record, indexing in progress

Family Accession:

Select item 3474683.

new record, indexing in progress

Family Accession:

Select item 235554.

dUTP diphosphatase

Gene:: dut

GO Terms:

Molecular Function:: magnesium ion binding (GO:0000287)

Molecular Function:: dUTP diphosphatase activity (GO:0004170)

Biological Process:: dUMP biosynthetic process (GO:0006226)

Biological Process:: dUTP catabolic process (GO:0046081)

Date:: 2021-07-22

Family Accession:: NF001862.0
Method:: HMM

Select item 218545.

dUTP diphosphatase

The main function of these proteins is in maintaining the levels of dUTP in the cell to prevent dUTP incorporation into DNA during DNA replication. The enzyme occurs in bacteria, viruses including prophage regions, and eukaryotes.