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substrate-binding domain-containing protein
This family includes bacterial extracellular solute-binding proteins. (from Pfam)
ABC transporter substrate-binding protein
extracellular solute-binding protein
This family also includes the bacterial extracellular solute-binding protein family POTD/POTF. [1]. 2002054. The 2.3-A resolution structure of the maltose- or maltodextrin-binding protein, a primary receptor of bacterial active transport and chemotaxis. Spurlino JC, Lu GY, Quiocho FA;. J Biol Chem 1991;266:5202-5219. [2]. 9360608. Structure of Haemophilus influenzae Fe(+3)-binding protein reveals convergent evolution within a superfamily. Bruns CM, Nowalk AJ, Arvai AS, McTigue MA, Vaughan KG, Mietzner TA, McRee DE;. Nat Struct Biol 1997;4:919-924. [3]. 9651355. Crystal structure and mutational analysis of the Escherichia coli putrescine receptor. Structural basis for substrate specificity. Vassylyev DG, Tomitori H, Kashiwagi K, Morikawa K, Igarashi K;. J Biol Chem 1998;273:17604-17609. [4]. 8336670. Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria. Tam R, Saier MH Jr;. Microbiol Rev 1993;57:320-346. (from Pfam)
ABC transporter substrate-binding protein functions as the initial receptor in the ABC transport of one or more from a variety of substrates such as amino acids, peptides, sugars, vitamins, and inorganic ions; similar to Actinobacillus pleuropneumoniae AfuA that is part of the AfuABC cyclic hexose/heptose-phosphate transporter; belongs to the type 2 PBP (PBP2) family
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