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nucleotide disphospho-sugar-binding domain-containing protein
This domain is found at the C-terminal of Erythromycin biosynthesis protein CIII (EryCIII) from Saccharopolyspora erythraea and similar proteins found in bacteria and eukaryotes. This protein is organised into two domains, both of them with a Rossmann-like alpha/beta fold. The C-terminal domain contains the nucleotide disphospho-sugar (NDP-sugar) binding site [1]. [1]. 22056329. Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII. Moncrieffe MC, Fernandez MJ, Spiteller D, Matsumura H, Gay NJ, Luisi BF, Leadlay PF;. J Mol Biol. 2012;415:92-101. (from Pfam)
glycosyltransferase
glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds
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