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TolC family protein
The OEP family (Outer membrane efflux protein) form trimeric channels that allow export of a variety of substrates in Gram negative bacteria. Each member of this family is composed of two repeats. The trimeric channel is composed of a 12 stranded all beta sheet barrel that spans the outer membrane, and a long all helical barrel that spans the periplasm. [1]. 10092468. Alignment and structure prediction of divergent protein families: periplasmic and outer membrane proteins of bacterial efflux pumps. Johnson JM, Church GM;. J Mol Biol 1999;287:695-715. (from Pfam)
TolC family protein is an outer membrane efflux protein that participates in type I protein secretion
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