Protein Family Models

This family consists of preprotein translocase subunit SecB. SecB is required for the normal export of envelope proteins out of the cell cytoplasm [1]. [1]. 2656409. Characterization of the Escherichia coli protein-export gene secB. Kumamoto CA, Nault AK;. Gene 1989;75:167-175. (from Pfam)

Date:

2024-10-16

Gene:

secB

Date:

2021-09-22

protein-export chaperone SecB, a component of the multisubunit membrane-bound enzyme Sec protein translocase, functions as an export-specific molecular chaperone that selectively binds preproteins, maintains them in a translocation competent state and delivers them to SecA, the membrane-bound ATPase that drives the translocation reaction

Date:

2023-10-03

This protein acts as an export-specific cytosolic chaperone. It binds the mature region of pre-proteins destined for secretion, prevents aggregation, and delivers them to SecA. This protein is tetrameric in E. coli. The archaeal Methanococcus jannaschii homolog MJ0357 has been shown (PMID:14985117) to share many properties, including chaperone-like activity, and scores between trusted and noise.

Gene:

secB

Date:

2021-04-27