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paraquat-inducible protein A
Paraquat is a superoxide radical-generating agent. The promoter for the pqiA gene is also inducible by other known superoxide generators [1]. This is predicted to be a family of integral membrane proteins, possibly located in the inner membrane. This family is related to NADH dehydrogenase subunit 2 (Pfam:PF00361). [1]. 7751275. Isolation of a novel paraquat-inducible (pqi) gene regulated by the soxRS locus in Escherichia coli. Koh YS, Roe JH;. J Bacteriol 1995;177:2673-2678. (from Pfam)
paraquat-inducible membrane protein A
membrane integrity lipid transport subunit YebS
YebS, as described in E. coli, is a paralog of PqiA and the partner of YebT (a paralog of PqiB) in a putative lipid transport system important to outer membrane integrity. Because of the similarity of the repeated MCE domains YebT and PqiB to MlaD of the Mla system involved in intermembrane transport of phospholipids, and lipid-binding activity of YebT and PqiB, YebST is classified by TCDB into the Intermembrane Phospholipid Translocase (IMPL-T) family, 9.A.69.
PqiA/YebS family transporter subunit
This family consists of uncharacterized predicted integral membrane proteins found, so far, only in the Proteobacteria. Of two members in E. coli, one is induced by paraquat and is designated PqiA, paraquat-inducible protein A.
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