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SfsA N-terminal OB domain
This family contains Sugar fermentation stimulation proteins. Which is probably a regulatory factor involved in maltose metabolism. This domain corresponds to the N-terminal OB fold. [1]. 2013578. Nucleotide sequence and characterization of the sfs1 gene: sfs1 is involved in CRP*-dependent mal gene expression in Escherichia coli. Kawamukai M, Utsumi R, Takeda K, Higashi A, Matsuda H, Choi YL, Komano T;. J Bacteriol 1991;173:2644-2648. [2]. 11272834. Effects of the Escherichia coli sfsA gene on mal genes expression and a DNA binding activity of SfsA. Takeda K, Akimoto C, Kawamukai M;. Biosci Biotechnol Biochem 2001;65:213-217. (from Pfam)
DNA/RNA nuclease SfsA
This family contains Sugar fermentation stimulation proteins. Which is probably a regulatory factor involved in maltose metabolism. SfsA has been shown to bind DNA [2] and it contains a helix-turn-helix motif that probably binds DNA at its C-terminus. [1]. 2013578. Nucleotide sequence and characterization of the sfs1 gene: sfs1 is involved in CRP*-dependent mal gene expression in Escherichia coli. Kawamukai M, Utsumi R, Takeda K, Higashi A, Matsuda H, Choi YL, Komano T;. J Bacteriol 1991;173:2644-2648. [2]. 11272834. Effects of the Escherichia coli sfsA gene on mal genes expression and a DNA binding activity of SfsA. Takeda K, Akimoto C, Kawamukai M;. Biosci Biotechnol Biochem 2001;65:213-217. (from Pfam)
DNA/RNA nuclease SfsA binds to DNA non-specifically and may be a regulatory factor involved in maltose metabolism
Members of this family are SfsA (sugar fermentation stimulation protein A), now recognized as a nuclease of the PD-(D/E)XK superfamily.
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