Protein Family Models

This is the N-terminal domain of Adaptive response protein AidB present in E. coli. AidB is upregulated in response to small doses of DNA-methylating agents initiates a response that mitigates the mutagenic and cytotoxic effects of DNA methylation. Tetramer formation is thought to be carried out by the N-terminal domain [1]. [1]. 22004173. Flavin-induced oligomerization in Escherichia coli adaptive response protein AidB. Hamill MJ, Jost M, Wong C, Elliott SJ, Drennan CL;. Biochemistry. 2011;50:10159-10169. (from Pfam)

Date:

2024-10-16

Date:

2024-08-14

Central domain of Acyl-CoA dehydrogenase has a beta-barrel fold. [1]. 7857927. Three-dimensional structure of butyryl-CoA dehydrogenase from Megasphaera elsdenii. Djordjevic S, Pace CP, Stankovich MT, Kim JJ;. Biochemistry. 1995;34:2163-2171. [2]. 8356049. Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate. Kim JJ, Wang M, Paschke R;. Proc Natl Acad Sci U S A 1993;90:7523-7527. (from Pfam)

Date:

2024-10-16

C-terminal domain of Acyl-CoA dehydrogenase is an all-alpha, four helical up-and-down bundle. [1]. 7857927. Three-dimensional structure of butyryl-CoA dehydrogenase from Megasphaera elsdenii. Djordjevic S, Pace CP, Stankovich MT, Kim JJ;. Biochemistry. 1995;34:2163-2171. [2]. 8356049. Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate. Kim JJ, Wang M, Paschke R;. Proc Natl Acad Sci U S A 1993;90:7523-7527. [3]. 11514662. Sequence-structure analysis of FAD-containing proteins. Dym O, Eisenberg D;. Protein Sci 2001;10:1712-1728. (from Pfam)

Date:

2024-10-16

Catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA

Date:

2021-08-24

acyl-CoA dehydrogenase family protein such as Escherichia coli AidB, which is involved in the SOS adaptive response to DNA alkylation damage

Date:

2018-04-13