Protein Family Models for Protein (Select 550756958) - Protein Family Models

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Items: 5

Select item 4125291.

glycine radical domain-containing protein

GO Terms:

Molecular Function:: catalytic activity (GO:0003824)

Date:: 2024-08-14

Family Accession:: NF013399.5
Method:: HMM

Select item 3901352.

new record, indexing in progress

Family Accession:

Select item 3473953.

new record, indexing in progress

Family Accession:

Select item 1485434.

autonomous glycyl radical cofactor GrcA

This small protein, previously designated YfiD in E. coli, is closely homologous to pyruvate formate_lyase (PFL) in a region surrounding the stable glycyl radical that is prepared by the action of pyruvate formate-lyase activase, a radical SAM enzyme. When damage at the site of this radical breaks the main chain of PFL, this protein acts as a spare part that reintroduces the needed stable glycyl radical. Cutoffs for this model are set to exclude a set of closely related phage proteins that appear to have a corresponding function.

Gene:: grcA

GO Terms:

Molecular Function:: catalytic activity (GO:0003824)

Date:: 2022-02-09

Family Accession:: TIGR04365.1
Method:: HMM

Select item 551915.

autonomous glycyl radical cofactor GrcA

autonomous glycyl radical cofactor GrcA is similar to pyruvate formate-lyase-activating protein and may act as a radical domain for damaged PFL or other radical proteins