Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
PafC helix-turn-helix domain
This entry is an N-terminal HTH domain found in the PafC protein. Transcriptional activator PafBC is responsible for upregulating the majority of genes induced by DNA damage [1]. [1]. 17277063. Characterization of the proteasome accessory factor (paf) operon in Mycobacterium tuberculosis. Festa RA, Pearce MJ, Darwin KH;. J Bacteriol. 2007;189:3044-3050. [2]. 31604936. Structure and functional implications of WYL domain-containing bacterial DNA damage response regulator PafBC. Muller AU, Leibundgut M, Ban N, Weber-Ban E;. Nat Commun. 2019;10:4653. (from Pfam)
WYL domain-containing protein
The WYL domain occurs regularly in CRISPR-associated (Cas) proteins.
helix-turn-helix transcriptional regulator
helix-turn-helix (HTH) transcriptional regulator containing DNA-binding HTH and WYL domains, may function in the regulation of DNA damage response and bacterial immunity
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on