Protein Family Models

MlaA is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane [1]. MlaA is required for the intercellular spreading of Shigella flexneri. It is attached to the outer membrane by a lipid anchor [2]. [1]. 19383799. An ABC transport system that maintains lipid asymmetry in the gram-negative outer membrane. Malinverni JC, Silhavy TJ;. Proc Natl Acad Sci U S A. 2009;106:8009-8014. [2]. 8145644. Identification and characterization of a chromosomal virulence gene, vacJ, required for intercellular spreading of Shigella flexneri. Suzuki T, Murai T, Fukuda I, Tobe T, Yoshikawa M, Sasakawa C;. Mol Microbiol 1994;11:31-41. (from Pfam)

Date:

2024-10-16

Gene:

mlaA

Date:

2022-02-18

phospholipid-binding lipoprotein MlaA actively prevents phospholipid accumulation at the cell surface

Date:

2018-01-09