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HD domain-containing protein
HD domains are metal dependent phosphohydrolases. [1]. 9868367. The HD domain defines a new superfamily of metal-dependent phosphohydrolases. Aravind L, Koonin EV;. Trends Biochem Sci 1998;23:469-472. (from Pfam)
HD domain-containing protein similar to Bacillus subtilis YqeK
bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK
Members of this family, called YqeK in species such as Staphylococcus aureus, function as a hydrolase of diadenosine tetraphosphate (Ap4A), cleaving symmetrically to yield two molecules of ADP. In contrast to ApaH (see TIGR00668), as found in E. coli, members of this family belong to the HD superfamily of hydrolases.
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