Protein Family Models for Protein (Select 567929973) - Protein Family Models

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Items: 5

Select item 4125501.

3-deoxy-7-phosphoheptulonate synthase

Members of this family are aldolase enzymes that catalyse the first step of the shikimate pathway. (from Pfam)

GO Terms:

Molecular Function:: 3-deoxy-7-phosphoheptulonate synthase activity (GO:0003849)

Biological Process:: aromatic amino acid family biosynthetic process (GO:0009073)

Date:: 2024-08-14

Family Accession:: NF013628.5
Method:: HMM

Select item 3921002.

new record, indexing in progress

Family Accession:

Select item 3484363.

new record, indexing in progress

Family Accession:

Select item 1419614.

class II 3-deoxy-7-phosphoheptulonate synthase

This HMM represents the class II family of 3-deoxy-7-phosphoheptulonate synthase, aka phospho-2-dehydro-3-deoxyheptonate aldolase, as found in plants and some bacteria. It shows some similarity to the class I family found in many bacteria. The enzyme catalyzes the first of 7 steps in the biosynthesis of chorismate, that last common precursor of all three aromatic amino acids. Homologs scoring between trusted and noise cutoff include proteins involved in antibiotic biosynthesis; one example is active as this enzyme, while another acts on an amino analog.

GO Terms: