Protein Family Models for Protein (Select 636833151) - Protein Family Models

Select item 4360651.

helix-turn-helix transcriptional regulator

helix-turn-helix (HTH) transcriptional regulator containing an N-terminal an autoinducer binding domain and a LuxR family HTH DNA-binding domain; may act as an activator or repressor in response to an inducer

Date:: 2024-12-07

Family Accession:: 12044921
Method:: Sparcle

Select item 4173292.

sigma factor-like helix-turn-helix DNA-binding protein

Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif [1]. [1]. 11931761. Structure of the bacterial RNA polymerase promoter specificity sigma subunit. Campbell EA, Muzzin O, Chlenov M, Sun JL, Olson CA, Weinman O, Trester-Zedlitz ML, Darst SA;. Mol Cell 2002;9:527-539. (from Pfam)

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Molecular Function:: DNA-binding transcription factor activity (GO:0003700)

Biological Process:: DNA-templated transcription initiation (GO:0006352)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Molecular Function:: sigma factor activity (GO:0016987)

Date:: 2024-10-16

Family Accession:: NF019886.5
Method:: HMM

Select item 4147093.

autoinducer binding domain-containing protein

This domain is found a a large family of transcriptional regulators. This domain specifically binds to autoinducer molecules (N-Acyl homoserine lactones, chlorolactone and rosmarinic acid) (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043). (from Pfam)

Date:: 2024-08-14

Family Accession:: NF015437.5
Method:: HMM

Select item 4118174.

LuxR C-terminal-related transcriptional regulator

GO Terms:

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2024-08-14

Family Accession:: NF012422.5
Method:: HMM

Select item 3972675.