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autonomous glycyl radical cofactor GrcA
autonomous glycyl radical cofactor GrcA is similar to pyruvate formate-lyase-activating protein and may act as a radical domain for damaged PFL or other radical proteins
glycine radical domain-containing protein
This small protein, previously designated YfiD in E. coli, is closely homologous to pyruvate formate_lyase (PFL) in a region surrounding the stable glycyl radical that is prepared by the action of pyruvate formate-lyase activase, a radical SAM enzyme. When damage at the site of this radical breaks the main chain of PFL, this protein acts as a spare part that reintroduces the needed stable glycyl radical. Cutoffs for this model are set to exclude a set of closely related phage proteins that appear to have a corresponding function.
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