Protein Family Models for Protein (Select 639234537) - Protein Family Models

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Links from Protein

Items: 7

Select item 4194661.

helix-turn-helix domain-containing protein

This family consists of several phage CI repressor proteins and related bacterial sequences. The CI repressor is known to function as a transcriptional switch, determining whether transcription is lytic or lysogenic [1]. [1]. 2370665. Control of gene expression in the temperate coliphage 186. VIII.. Control of lysis and lysogeny by a transcriptional switch. involving face-to-face promoters.. Dodd IB, Kalionis B, Egan JB;. J Mol Biol 1990;214:27-37. (from Pfam)

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Biological Process:: negative regulation of DNA-templated transcription (GO:0045892)

Date:: 2024-08-14

Family Accession:: NF018697.5
Method:: HMM

Select item 4125442.

helix-turn-helix domain-containing protein

This large family of DNA binding helix-turn helix proteins includes Cro Swiss:P03036 and CI Swiss:P03034. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family [1]. [1]. 20196080. The crystal structure of NGO0477 from Neisseria gonorrhoeae. reveals a novel protein fold incorporating a helix-turn-helix. motif.. Ren J, Sainsbury S, Nettleship JE, Saunders NJ, Owens RJ;. Proteins. 2010;78:1798-1802. (from Pfam)