Protein Family Models

This family was first named TPM domain after its founding proteins: TLP18.3, Psb32 and MOLO-1. In Arabidopsis, this domain is called the thylakoid acid phosphatase -TAP - domain and has a Rossmann-like fold [1]. In plants, the family resides in the thylakoid lumen attached to the outer membrane of the chloroplast/plastid. It is active in the photosystem II [2,3]. [1]. 21908686. Structural and Functional Assays of AtTLP18.3 Identify Its Novel Acid Phosphatase Activity in Thylakoid Lumen. Wu HY, Liu MS, Lin TP, Cheng YS;. Plant physiol. 2011;9:0-0. [2]. 17576201. TLP18.3, a novel thylakoid lumen protein regulating photosystem II repair cycle. Sirpio S, Allahverdiyeva Y, Suorsa M, Paakkarinen V, Vainonen J, Battchikova N, Aro EM;. Biochem J. 2007;406:415-425. [3]. 21653280. The Psb32 protein aids in repairing photodamaged photosystem II in the cyanobacterium Synechocystis 6803. Wegener KM, Bennewitz S, Oelmuller R, Pakrasi HB;. Mol Plant. 2011;4:1052-1061. (from Pfam)

Date:

2024-10-16

TPM (TLP18.3, Psb32 and MOLO-1) domain-containing protein may act as a phosphatase

Date:

2022-12-05