Protein Family Models for Protein (Select 647320406) - Protein Family Models

Select item 4252241.

protealysin propeptide domain-containing protein

This propeptide is cleaved during maturation of protealysin [1-2]. Before cleavage it interacts with the catalytic domain, blocking the active site [3]. [1]. 16442309. Cloning, sequencing, expression, and characterization of protealysin, a novel neutral proteinase from Serratia proteamaculans representing a new group of thermolysin-like proteases with short N-terminal region of precursor. Demidyuk IV, Kalashnikov AE, Gromova TY, Gasanov EV, Safina DR, Zabolotskaya MV, Rudenskaya GN, Kostrov SV;. Protein Expr Purif. 2006;47:551-561. [2]. 19324072. Processing of protealysin precursor. Gromova TY, Demidyuk IV, Kozlovskiy VI, Kuranova IP, Kostrov SV;. Biochimie. 2009;91:639-645. [3]. 19915005. Crystal structure of the protealysin precursor: insights into propeptide function. Demidyuk IV, Gromova TY, Polyakov KM, Melik-Adamyan WR, Kuranova IP, Kostrov SV;. J Biol Chem. 2010;285:2003-2013. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF027800.5
Method:: HMM

Select item 4135592.

Thermolysin metallopeptidase, catalytic domain

GO Terms:

Molecular Function:: metalloendopeptidase activity (GO:0004222)

Date:: 2024-08-14

Family Accession:: NF013604.5
Method:: HMM

Select item 4129953.

M4 family metallopeptidase

GO Terms:

Molecular Function:: metalloendopeptidase activity (GO:0004222)

Date:: 2024-08-14

Family Accession:: NF014869.5
Method:: HMM

Select item 4073804.